' Bruker's Ultraflextreme MALDI-TOF is able to be used for conventional proteomic analyses as well as MALDI Mass Spectrometry Imaging. This versatile mass spectrometer is able to achieve 2 kHz speed in MS mode and 1 kHz in MS2 being able to analyse and process samples in a fast, reliable way.

The UI of the software provided is user-friendly and, despite the parameter optimization being a complex procedure, the common user can achieve results after one month of training. I would definitely recommend it for laboratories interested in achieving consistent proteomics results: Bruker support is always available for troubleshooting and support. It's featured in countless publications, ranging from microbiology to plant proteomics, tumor heterogeneity and biomarker discovery studies. ' Review date: 31 Mar 2016 ultrafleXtreme™. ' UltrafleXtreme is well suited for imaging and profiling of large biomolecules especially lipids, peptides and proteins.

The instrument is easy to operate with detailed instructions in manual, robust and stable. The software is user friendly.

Service after sale is very good. For European countries, service can be provided almost right away. Technicians from company can observe and check out the instrument via internet. Generally, this instrument is excellent for routine analyses in metabolomics and proteomics with spatial resolution of imaging not better than 20 micrometer.'

Review date: 28 Apr 2015 ultrafleXtreme™. ' Bruker Utraflex MALDI-TOF/TOF-MS series are primarily designed for Proteomics application. It’s an outstanding easy to use instrument that works very stable for years long without significant problems and doesn't require many consumables. Flex analysis software generally required few minutes training to enable user to start acquiring spectra. Apart from Proteomics one by knowing the basics of LDI and TOF analyzers, can use instrument for the analysis of small molecules with extremely high throughput. Especially such instrument can be applied for species finger printing purposes with and without matrix approaches. It can deliver very sensitive and accurate measurements for small molecule if calibrated correctly.

People working in areas like matrix development, matrix free LDI, solution free LDI can try many different options to efficiently ionize the molecules of interest but such application required advance knowledge of instrument design which is generally not given out by vendors! ' Review date: 22 Apr 2014 ultrafleXtreme™. Attain the highest level of mass spectrometry performance with the ultrafleXtreme™, an instrument exceeding all your expectations. Solvent Demonstration Tape Raritan. The new ultrafleXtreme™ incorporates next-generation MALDI-TOF and TOF/TOF technology. Combining true 2kHz speed in both TOF and TOF/TOF modes with ultrahigh performance and extreme flexibility for a broad variety of complementary research, clinical and applied proteomics applications. UltrafleXtreme™ Features: • Innovative smartbeam-II™ laser enables ultra-high data acquisition speed in both MS and MS/MS at full systems performance. • Laser focus diameters down to 10 µm for high spatial resolution imaging without pixel overlap.

• Mass resolving power up to 40,000 and 1.5 ppm mass accuracy for highest confidence. • Unique laser-irradiation self-cleaning Ion Source ensures robust, long-term highest-performance operation.

• The high efficiency and sensitivity of MS/MS process delivers TOF/TOF spectra with nominal mass resolution for peptides. Users Manual For Philips Cardiomd.

The UltrafleXtreme incorporates next-generation MALDI-TOF and TOF/TOF technology: • The innovative smartbeam-II™ laser enables ultra-high data acquisition speed in both MS and MS/MS at full systems performance. The well-established proprietary smartbeam laser provides unprecedented analytical and matrix flexibility in workflows from protein tissue imaging, intact proteins analysis, biologics or oligo QC, to LC-MALDI proteomics - all fully enabled at 1-1000 Hz repetition rates. • Bruker's patented smartbeam technology is already widely accepted as the most viable MALDI imaging laser technology. The ultrafleXtreme now enables laser focus diameters down to 10 µm for high spatial resolution imaging without pixel overlap. Importantly, outstanding spectral quality and signal intensity are maintained at even the smallest laser beam diameters. • Broadband mass resolving power up to 40,000 enables precision proteomics via Bruker’s unique PAN™ technology for highest mass resolution across a very broad mass range, not just at a selected optimum. • The novel FlashDetector™ combined with a new 4 GHz digitizer and latest advances in electronics provide unmatched mass resolving power up to 40,000 and 1 ppm mass accuracy for highest confidence.

[PDF] bruker apex 2 manual (28 pages) - rayos x instrumentaci 243 n cient 237 fica, max3d. Bruker Ultraflextreme Manual Version Free Software. Ultrafle treme Beyond Imagination The new 2 16956 m/z. The new ultrafleXtreme. Bruker DHAP matrix proven for Top-Down analysis producing multiple.

• The novel and unique laser-irradiation self-cleaning MALDI Perpetual™ Ion Source ensures robust, long-term highest-performance operation. Very long MALDI laser lifetime in combination with automated source cleaning in just minutes leads to high uptime and low maintenance costs. • Latest TOF/TOF technology: The high efficiency and sensitivity of the LID-LIFT process delivers MS/MS spectra with nominal mass resolution for peptides. Typically, full MS/MS data sets can be acquired from low fmol levels within seconds.

The Bruker bioinformatic software is perfectly adapted to analyze and visualize the match between the raw spectra and annotated peptide and protein structures As a result, proteins can be identified with high confidence with unmatched ease. --- Adopted from Bruker Daltonics website.